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Background and objective: The rate of end-stage renal disorder (ESRD) in Iran, 12%, is more than the worldwide range. The people with Hemodialysis are greatly under physical, mental and social pressures that make the acceptance of Hemodialysis difficult. Since the acceptance can be the beginning point of adaptation, this study aimed to explore the challenge in acceptance of Hemodialysis.
Material and Methods: This grounded theory study was undertaken in the Hemodialysis wards of the hospitals affiliated with Shaheed Beheshti University of Medical Sciences in Tehran. The first samples were selected via purposive sampling and the later ones with theoretical sampling till data saturation (N=24).‌ Semi-structured interview, field notes and memos were used for data collection. The data was analyzed by using Strauss and Corbin method. Data rigor was confirmed by Lincoln and Goba criteria, considering ethical points. Results: The challenge in acceptance of Hemodialysis emerged the categories of acceptance (by force, experience, reasoning or social norms) and lack of acceptance (subjective or objective) of necessity of Hemodialysis as well as their related codes.
 Conclusion: The people on Hemodialysis encounter a challenge for acceptance of Hemodialysis. Education as well as personal, familial and social supports can resolve this challenge by changing lack of acceptance (subjective or objective) or acceptance by force to acceptance (by experience, reasoning or social norms).

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Background: Human Papilloma Virus (HPV) is the causative agent of cervical cancer. Vaccination against HPV is an effective strategy against cervical cancer. This study aimed to assess the acceptance of HPV vaccination for cervical cancer prevention and its relationship with knowledge and attitude about HPV vaccination among students.
Methods: This cross-sectional study was carried out on 360 female students at Bushehr University of Medical Sciences in 2018. Students were recruited using proportional stratified random sampling method. Data was gathered using a questionnaire about knowledge, attitude and effective factors of HPV vaccine acceptance. Descriptive analysis, chi-square, independent sample t-test, and logistic regression were used to analyze the data in SPSS-16.0 (SPSS Inc., Chicago, IL, USA).  The significance level was set at P < 0.05.
Results: 56.4% of students had poor knowledge while 54.1% were willing to accept HPV vaccination as well as 43% who had positive attitude towards HPV vaccination. Paramedical students were 96% more likely to accept the HPV vaccination compared to health sciences faculty students (OR= 1.96; 95% CI= 1.04-3.68; p=0.036).  Also, for each unit increase in the HPV knowledge score, students were 15% more likely to accept the vaccine (OR= 1.15; 95% CI= 1.07-1.24; p <0.001). Moreover, for each unit increase in attitude score, students were 16% more likely willing to accept HPV vaccine (OR= 1.16; 95% CI=1.08 -1.28; p =0.002).
Conclusions: It is necessary to implement on HPV vaccination for students. Inclusion of HPV vaccine in the National Program on Immunization would also be an effective strategy for improving HPV vaccination.